If you are running openSUSE 11.2, it's quite simple to safely update your entire Mono stack and stay up to date with any 2.6 updates:
zypper ar -f -n Mono http://ftp.novell.com/pub/mono/download-stable/openSUSE_11.2 repo-mono
zypper mr -p 10 repo-mono
zypper dup -r repo-mono
Those instructions will change the Mono distribution from openSUSE to the upstream Mono repositories.
I highly recommend installing MonoDevelop 2.2 (
zypper in monodevelop), though if you already had it installed, the above will update you to the 2.2 release.
A huge congratulations and thank you to the Mono team for another exceptional major Mono milestone!
UPDATE: apparently there is a problem on the x86_64 build in the openSUSE Build Service. This appears to be an OBS bug, but for this reason, it's recommended that you use the repositories at http://ftp.novell.com/pub/mono/download-stable.